Handsome Jack is the main antagonist of Borderlands 2, and the deuteragonist of Borderlands: The Pre-Sequel. He has taken over the Hyperion corporation, declared himself dictator of Pandora, and stolen all of the credit for finding The Vault, going so far as to claim responsibility for killing The Destroyer. A new team of Vault Hunters is tasked with killing Jack and restoring (relative) peace to Pandora.

Jack placed Helios, an enormous geostationary space station, in the Lagrange point between Pandora and its moon, Elpis. It acts as an homage to his ego as well as a supply base from which he can send supplies and troops down to Pandora. The satellite also has a lens that allows Jack to keep an eye on the Vault Hunters at all times.